Endometrial Cancer

Endometrial Cancer

Endometrial cancer is cancer that starts in the endometrium, which is the lining of the uterus.

Causes:

Cancer occurs between the ages of 60 and 70 years, but a few cases may occur before age 40.

The following increase your risk of endometrial cancer:

Tamoxifen, a drug for breast cancer treatment

Never being pregnant

Obesity

Starting menstruation at an early age (before age 12)

Starting menopause after age 50

Diabetes

Estrogen replacement therapy without the use of progesterone

History of endometrial polyps or other benign growths of the uterine lining

Infertility (inability to become pregnant)

Associated conditions include the following:

Colon or breast cancer

Hypertension

Polycystic ovarian disease

Symptoms:

Abnormal uterine bleeding, abnormal menstrual periods:

Bleeding between normal periods before menopause

Vaginal bleeding or spotting after menopause

Extremely long, heavy, or frequent episodes of vaginal bleeding after age 40

Lower abdominal pain or pelvic cramping

Thin white or clear vaginal discharge after menopause

Diagnosis:

Endometrial aspiration or biopsy

Dilation and curettage (D and C)

Pap smear

Treatment:

Treatment options involve surgery, radiation therapy, and chemotherapy.

A hysterectomy may be performed in women with the early stage 1 disease. Removal of the tubes and ovaries (bilateral salpingo-oophorectomy) is also usually recommended.

Chemotherapy considered in some cases, especially for those with stage 3 and 4 disease.

Prognosis:

The 1-year survival rate is about 92%.

The 5-year survival rate for endometrial cancer that has not spread is 95%. If the cancer has spread to distant organs, the 5-year survival rate drops to 23%.

When to Contact us:

If you have abnormal vaginal bleeding or spotting after intercourse or douching:

Bleeding lasting longer than 7 days

Periods that occur every 21 days or more

Bleeding or spotting after 6 months or more of no bleeding at all

Prevention:

All women should have regular pelvic exams beginning at the onset of sexual activity.

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